England’s women were thrashed by India, who sealed a series victory with a seven-wicket win in the second one-day international in Mumbai.
The tourists slumped to 44-4 and 95-7, only recovering to 161 through a last-wicket stand of 42 between Nat Sciver (85) and Alex Hartley.
India were barely troubled in the chase, Smriti Mandhana’s 63 helping them home with almost nine overs left.
The third and final match in the series is on Thursday.
With the chance of winning a first series in India gone, England can still earn valuable points in the International Cricket Council’s Women’s Championship., external
The opening two defeats have kept them in seventh place, with only the top four qualifying for the 2021 World Cup at the earliest opportunity.
After 11 games, the 2017 world champions have won five and lost six.
With series against Sri Lanka, West Indies and Pakistan to come, England’s fate remains in their own hands, but another defeat in India would leave little room for manoeuvre.
Captain Heather Knight told BBC Sport: “We haven’t given a true account of ourselves, and that’s disappointing. We haven’t played well enough.
“The series has gone now, but we have one more game with Championship points on offer. We have to move on and focus on the last ODI.
“I don’t think we have played anywhere near as we can as a team and that is frustrating. I guess it does put a little bit of pressure us in terms of the Championship and that is our own doing. We’ll have to scrap hard to get those points.”