Down are the only Ulster side competing in the 2021 All-Ireland senior division and continue their campaign against a confident Cork squad on Saturday.
Waterford edged a one-point win over the Mourne women in the competition’s first round, but the Ulster champions were in the lead for most of the match with plenty of points including nine from Niamh Mallon.
Having home advantage at Pairc Esler may be of some comfort to Derek Dunne’s side, who were promoted to the top-flight at the end of the 2020 season.
However Cork will arrive in Newry in a confident mood following their 13-point opening victory against Dublin.
Down have never won an All-Ireland camogie title at senior level and have only once made it to a final once, in 1948 against Dublin.