Kingsholm, which was chosen to host the final well in advance of Gloucester’s success, will likely be packed for the game.
It will end a season which has seen women’s rugby union in England once again increase in visibility thanks to the Red Roses making the World Cup final and their Six Nations success.
But with the men’s game suffering major financial concerns – London Irish went into administration earlier this month and the top flight lost Wasps and Worcester last season – is a professional women’s game in England sustainable?
“This league is the best in the world, there’s showcase games every single week,” says Appleby.
“The game is going from strength to strength. How sustainable is it? It’s as sustainable as we make it.
“We put in a lot of work, it doesn’t just happen, this club works really hard to make it happen.
“[Exeter chief executive] Tony Rowe’s a businessman, so were really conscious that we want to make it the best that we can for Tony and everything that he’s invested.
“The RFU have put down very stringent rules around a salary cap and that will stop, they believe, what has happened in the men’s game where it gets out of control and clubs go under, so they’ve learned a lot of lessons from what’s gone before.”
Exeter beat Gloucester 58-19 a few weeks ago, but the Cherry and Whites rested a host of their international players for the fixture.
Despite that, Appleby is confident her squad gained a good sense of what they will face as both sides aim for a maiden title.
“We still beat a good Gloucester side, a strong Gloucester side,” she says.
“We learned some things about their style of play, so it was a valuable experience, probably an important win for us.
“We only played them recently, but it doesn’t really matter what’s gone before, the main thing is the big focus on the final.”